4-Quinazolinamine, 2-chloro-5-iodo-
2-chloro-5-iodoquinazolin-4-amine
CAS: 1107694-85-8
Molecular Formula: C8H5ClIN3
4-Quinazolinamine, 2-chloro-5-iodo- - Names and Identifiers
| Name | 2-chloro-5-iodoquinazolin-4-amine |
| Synonyms | 2-chloro-5-iodoquinazolin-4-aMine 2-chloro-5-iodoquinazolin-4-amine 2-Chloro-5-iodo-4-quinazolinamine 4-Quinazolinamine, 2-chloro-5-iodo- |
| CAS | 1107694-85-8 |
4-Quinazolinamine, 2-chloro-5-iodo- - Physico-chemical Properties
| Molecular Formula | C8H5ClIN3 |
| Molar Mass | 305.5 |
| Density | 2.088±0.06 g/cm3(Predicted) |
| Boling Point | 392.2±24.0 °C(Predicted) |
| pKa | 3.78±0.30(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD11858260 |
4-Quinazolinamine, 2-chloro-5-iodo- - Introduction
2-Chloro-4-amino-5-iodoquinazoline is an organic compound with the chemical formula C8H5ClIN3. It has the following characteristics and properties:
1. Appearance: 2-chloro-4-amino-5-iodoquinazoline is a white to light yellow crystalline powder.
2. Melting point: It has a higher melting point, about 220-223 ℃.
3. Solubility: It can be well dissolved in common organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane (DCM) and acetonitrile.
The main uses of 2-chloro-4-amino-5-iodoquinazoline are as follows:
1. Pharmaceutical field: It is an important intermediate compound, which can be used to synthesize biologically active compounds, such as antibacterial drugs, anti-tumor drugs, etc.
The method for preparing 2-chloro-4-amino-5-iodoquinazoline is as follows:
1. It is usually prepared by reacting 4-amino -5-iodoquinazoline with chloroacetyl chloride. The reaction is carried out under an inert atmosphere, such as nitrogen.
For the safety information of 2-chloro-4-amino-5-iodoquinazoline, the following are some important considerations:
1. Toxicity: 2-chloro-4-amino-5-iodoquinazoline is an organic chlorine compound with certain toxicity. Care should be taken during use to avoid direct contact with skin, eyes and respiratory tract.
2. Environmental impact: 2-chloro-4-amino-5-iodoquinazoline may cause certain environmental pollution to water and soil. Waste shall be disposed of in accordance with the relevant regulations.
3. storage conditions: 2-chloro -4-amino -5-iodoquinazoline should be stored in a dry, cool place, and away from fire and oxidant.
When using and handling 2-chloro-4-amino-5-iodoquinazoline, follow relevant safety procedures and handle it in accordance with local regulations.
1. Appearance: 2-chloro-4-amino-5-iodoquinazoline is a white to light yellow crystalline powder.
2. Melting point: It has a higher melting point, about 220-223 ℃.
3. Solubility: It can be well dissolved in common organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane (DCM) and acetonitrile.
The main uses of 2-chloro-4-amino-5-iodoquinazoline are as follows:
1. Pharmaceutical field: It is an important intermediate compound, which can be used to synthesize biologically active compounds, such as antibacterial drugs, anti-tumor drugs, etc.
The method for preparing 2-chloro-4-amino-5-iodoquinazoline is as follows:
1. It is usually prepared by reacting 4-amino -5-iodoquinazoline with chloroacetyl chloride. The reaction is carried out under an inert atmosphere, such as nitrogen.
For the safety information of 2-chloro-4-amino-5-iodoquinazoline, the following are some important considerations:
1. Toxicity: 2-chloro-4-amino-5-iodoquinazoline is an organic chlorine compound with certain toxicity. Care should be taken during use to avoid direct contact with skin, eyes and respiratory tract.
2. Environmental impact: 2-chloro-4-amino-5-iodoquinazoline may cause certain environmental pollution to water and soil. Waste shall be disposed of in accordance with the relevant regulations.
3. storage conditions: 2-chloro -4-amino -5-iodoquinazoline should be stored in a dry, cool place, and away from fire and oxidant.
When using and handling 2-chloro-4-amino-5-iodoquinazoline, follow relevant safety procedures and handle it in accordance with local regulations.
Last Update：2024-04-09 18:58:34
